Does Damiana Leaf Increase Testosterone or Amplify Estrogen?


Damiana leaf has started to appear more frequently in natural testosterone boosters but the validity to the claims are suspect at best.

Native to Mexico, the Aztec and Mayan Indians used damiana as an aphrodisiac for both Men and Women.

Unfortunately, the scientific community knows very little about the herb. There are a few case studies on rats but we couldn’t locate any human based studies done solely with damania.

To muddy the waters even further, out of the handful of studies to date, many of them used additional compounds in the testing. There is simply no way to know for sure if damania played a critical role in any positive results.

Can Science Validate Damiana?

There are no reliable studies on humans so far since other herbs were mixed in with any studies performed but there are some positive tests on rats.

For example, when damania is given to sexually exhausted male rats, it works as an aphrodisiac for them, lessening the time it takes them to become aroused again. However, it doesn’t appear to do anything to rats not suffering from sexual exhaustion. (1, 2)

As we frequently say here at iTestosterone, rats are not humans so that’s not a whole lot to go on. But we do not want to discredit the Aztec wonder herb yet as sometimes science takes awhile to catch up to an ancient folk remedy.

Is Damiana a Testosterone Booster or Estrogen Amplifier?

In a recent case study, 78 men suffering with sexual dysfunction were given 200 mg of damiana along with a mix of other herbs. An improvement in erectile function was seen over the placebo group, however, the part we want to highlight here is no change in testosterone levels were noted. (3)

Another lab based study found damiana to be both anti-estrogenic and estrogenic at the same time.

It found two isolated compounds, pinocembrin and acacetin which may suppress aromatase activity, which is the body’s conversion of testosterone to estrogen.

However other compounds, apigenin 7-glucoside, Z-echinacin and oddly enough pinocembrin again, showed an increase in estrogenic activity.

With a lack of further human research there is no way to say for sure exactly what damiana does. But we can safely conclude at this point in time, there is no reason to suspect it provides any increase in testosterone levels.

What About Damiana For Women?

Many women have reported successfully taking damiana to help regulate periods, improve postmenopausal symptoms, increase arousal and strength of orgasm.


The jury is still out on how effective damiana is for a man’s testosterone levels but based on the evidence at hand, you shouldn’t expect to see any results from it.

For women, a lack of scientific evidence still prevails but anecdotal evidence abounds which kind of makes sense given the strange and fairly unique anti-estrogenic and estrogenic mix damiana appears to have.

Alpha Wolf Testosterone Force X7

Force X7 by Alpha Wolf Nutrition is the only multi-ingredient, natural T booster we recommend.

Increase strength, stamina and muscle size.

Use coupon code “itestosterone” for 10% off your purchase! Click here to learn more.



  1. Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males. Estrada-Reyes R, Ortiz-López P, Gutiérrez-Ortíz J, Martínez-Mota L – Link
  2. Stimulating property of Turnera diffusa and Pfaffia paniculata extracts on the sexual-behavior of male rats. Arletti R, Benelli A, Cavazzuti E, Scarpetta G, Bertolini A. – Link
  3. Evaluation of a multi-herb supplement for erectile dysfunction: a randomized double-blind, placebo-controlled study. Gaurang R Shah, Manojkumar V Chaudhari, Suresh B Patankar, Shrikant V Pensalwar, Vilas P Sabale, Navneet A Sonawane – Link


Previous articleFasting Increases Testosterone Levels: Here’s How
Next articleAlpha JYM Review – Jim Stoppani’s Test Booster Misses the Mark
Ted McKenzie is a fitness enthusiast, blogger, and health advocate. Through his blog, he inspires and empowers individuals to prioritize their health and embark on fulfilling fitness journeys. With expertise in strength training, nutrition, mindfulness, and exercise science, Ted offers valuable information, practical tips, and evidence-based guidance. His holistic approach emphasizes balance, sustainability, and mental well-being. Join Ted on his journey to discover practical strategies, motivation, and reliable resources for achieving fitness goals.